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KMID : 1239420140050010026
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Journal of Orthopaedic Pain Society
2014 Volume.5 No. 1 p.26 ~ p.32
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The Effect of Selective COX-2 Inhibitor on Pain Control following Arthroscopic Rotator Cuff Repair - A Preliminary Report of Prospective Randomized Comparative Study -
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Choi Hye-Yeun
Seo Hyuk-Jun
Lee Ye-Hyun
Ha Jae-Hong
Oh Joo-Han
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Abstract
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Purpose: To evaluate selective COX-2 inhibitor as a postoperative analgesics, compared to Ibuprofen, a commonly used NSAID, and Tramadol, an opioid, in patients undergoing arthroscopic rotator cuff repair.
Materials and Methods: One hundred and eighty patients scheduled for arthroscopic rotator cuff repair from September 2011 to August 2012 were prospectively enrolled. Sixty patients were randomly assigned to Celecoxib, Ibuprofen, and Tramadol prescribed groups, respectively. They were followed up until 2 weeks postoperatively. Visual analogue scale(VAS) for pain, patient satisfaction VAS for pain control, various side effects from the prescribed analgesics, and additional use of rescue medication were recorded, and compared at 3 days and 2 weeks postoperatively
Results: 63 male and 117 female patients were included in the study with a mean age of 60.8±9.1 years. There were no significant differences between three groups with respect to demographic factors such as age, sex, underlying illnesses,
and the size of rotator cuff tear. Preoperative pain VAS were 6.5, 6.7, 6.1 for Celecoxib, Ibuprofen, and Tramadol groups respectively, and improved to 3.4, 3.8, 4.0 at postoperative 3 days and 2.8, 3.2, 3.2 at postoperative 2 weeks, respectively (all p>0.05). There were no statistically significant differences between the three groups regarding adverse effects and amount of rescue medication used, although the Tramadol group showed a higher tendency of gastrointestinal problems at postoperative 3 days and daytime somnolence at postoperative 2 weeks.
Conclusion: Selective COX-2 inhibitors showed similar efficacy compared with Ibuprofen and Tramadol-based analgesics
in postoperative pain control and patient satisfaction after arthroscopic rotator cuff repair.
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KEYWORD
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Rotator cuff tear, Arthroscopic rotator cuff repair, Postoperative analgesic, Selective COX-2 inhibitor
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